Discovering the Best: 43 Skincare Brands That Have Been Best-Sellers for Decades
In the ever-evolving world of skincare, it can be overwhelming to keep up with the latest trends and products. But amidst all the new and flashy brands, there are some tried and true skincare brands that have been best-sellers for decades. These brands have stood the test of time and continue to deliver effective and reliable products that have become staples in many people’s skincare routines.
In this blog post, we will take a closer look at 43 of these best-selling skincare brands. From drugstore favorites to high-end luxury brands, we will explore the history, key products, and customer reviews of each brand to uncover what makes them stand out in the crowded skincare market. So let’s dive in and discover the best of the best in skincare!
1. Neutrogena
Founded in 1930, Neutrogena has been a trusted name in skincare for over 90 years. Their commitment to science and innovation has led to the development of a wide range of skincare products, including the iconic Neutrogena Oil-Free Acne Wash and Hydro Boost Gel Cream. With a focus on gentle yet effective formulas, Neutrogena has become a go-to brand for many skincare enthusiasts.
2. Olay
Another brand with a long history, Olay was founded in 1952 and has since become a household name in the world of skincare. Their anti-aging products, such as the Regenerist Micro-Sculpting Cream, are widely praised for their results. Olay also offers a range of affordable and accessible skincare options, making it a favorite among consumers.
3. Clinique
Clinique was born in 1968, with the mission to create products free from known allergens, irritants, and harsh ingredients. Their 3-Step Skincare System, which includes a cleanser, toner, and moisturizer, has been a best-seller for decades. With a focus on catering to different skin types and concerns, Clinique has become a go-to brand for those with sensitive skin.
4. Estée Lauder
Founded in 1946, Estée Lauder has become one of the most recognizable luxury skincare brands in the world. Their Advanced Night Repair Serum is a cult favorite, with many customers swearing by its anti-aging benefits. With a focus on high-quality ingredients and innovative formulations, Estée Lauder has cemented its place as a top skincare brand.
5. L’Oréal Paris
L’Oréal Paris is one of the largest and most well-known beauty brands in the world, with a history that dates back to 1909. Their skincare range includes everything from anti-aging creams to acne treatments, all at an affordable price point. The brand’s dedication to science and research has led to the development of effective and accessible products, making it a favorite among consumers.
6. Cetaphil
Cetaphil was founded in 1947 by a pharmacist who wanted to create a gentle and effective cleanser for his patients. Today, their Gentle Skin Cleanser is a best-seller and has become a staple for those with sensitive skin. With a focus on simplicity and effectiveness, Cetaphil has become a trusted brand for those looking for gentle skincare solutions.
7. Kiehl’s
Kiehl’s was founded in 1851 as an apothecary in New York City, making it one of the oldest skincare brands on our list. With a strong commitment to using natural ingredients, the brand has become known for its effective and luxurious products. Their Ultra Facial Cream is a best-seller and has been praised for its hydrating and anti-aging benefits.
8. Dermalogica
Founded in 1986 by a skin therapist, Dermalogica has become a go-to brand for professional-grade skincare. With a focus on education and customized solutions for different skin concerns, their products have gained a loyal following. The Daily Microfoliant and Special Cleansing Gel are just a few of their best-selling products that have won over many skincare enthusiasts.
9. La Roche-Posay
La Roche-Posay is a French skincare brand that was founded in 1975 and is known for its dermatologist-tested products. Their Anthelios Sunscreen line is a top-seller and has been praised for its high sun protection factor and lightweight formulas. With a focus on sensitive and acne-prone skin, La Roche-Posay has become a trusted brand for those with specific skincare concerns.
10. Aveeno
Aveeno was founded in 1945 and has become a popular brand for its use of natural ingredients, particularly oatmeal. Their Daily Moisturizing Lotion is a best-seller and has been praised for its ability to hydrate and soothe dry skin. With a focus on gentle and effective formulas, Aveeno has become a go-to brand for those with sensitive skin.

Discovering the Best: 43 Skincare Brands That Have Been Best-Sellers for Decades
11. Biotherm
Biotherm was founded in 1952 and has since become a top skincare brand in Europe. The brand’s use of thermal plankton, a natural ingredient found in the French Pyrenees, has become its signature. Their Life Plankton Essence and Aquasource Gel are just a few of their best-selling products that have gained a loyal following for their hydrating and anti-aging benefits.
12. Shiseido
Founded in 1872, Shiseido is one of the oldest skincare brands in the world. The Japanese brand has become known for its use of traditional Japanese ingredients, such as green tea and rice, in their products. The Ultimune Power Infusing Concentrate and Benefiance WrinkleResist24 Intensive Eye Contour Cream are just a few of their best-selling products that have gained a cult following for their anti-aging benefits.
13. Mario Badescu
Mario Badescu was founded in 1967 and has become a go-to brand for affordable and effective skincare solutions. With a focus on using natural ingredients, their products have gained a loyal following for their ability to target specific skin concerns. The Drying Lotion and Facial Spray with Aloe, Herbs, and Rosewater are two of their best-selling products that have become staples in many people’s skincare routines.
14. CeraVe
CeraVe was founded in 2005 and has quickly become a favorite among skincare enthusiasts. The brand’s use of ceramides, a natural ingredient that helps to restore and protect the skin’s barrier, has gained praise for its effectiveness. Their Hydrating Cleanser and Moisturizing Cream are two of their best-selling products that have become staples for those with dry and sensitive skin.
15. Bioderma
Bioderma is a French skincare brand that was founded in the 1970s and has since become a top brand in Europe. Their micellar water, Sensibio H2O, has gained a cult following for its gentle yet effective makeup removing abilities. With a focus on sensitive skin, Bioderma has become a trusted brand for those looking for gentle and effective skincare solutions.
16. Murad
Founded in 1989 by a dermatologist, Murad has become a go-to brand for professional-grade skincare. The brand’s use of advanced technology and high-quality ingredients has led to the development of effective and luxurious products. Their Retinol Youth Renewal Serum and Essential-C Day Moisture are two of their best-selling products that have gained a loyal following for their anti-aging benefits.
17. The Body Shop
The Body Shop was founded in 1976 and has become a global brand known for its commitment to ethical and sustainable practices. Their Tea Tree Oil line is a best-seller and has been praised for its ability to target and treat acne-prone skin. With a focus on natural and cruelty-free ingredients, The Body Shop has become a favorite among those looking for eco-friendly skincare options.
18. Skinceuticals
Skinceuticals was founded in 1997 and has since become a top brand for professional-grade skincare. Their use of high concentrations of active ingredients has gained praise for its effectiveness in treating various skin concerns. The C E Ferulic Serum and Hydrating B5 Gel are two of their best-selling products that have gained a loyal following for their anti-aging benefits.
19. Origins
Origins was founded in 1990 with the mission to create high-performance, natural skincare products. The brand’s use of plant-based ingredients has led to the development of effective and gentle products. Their GinZing Energy-Boosting Gel Moisturizer and Original Skin Retexturizing Mask with Rose Clay are two of their best-selling products that have gained a loyal following for their ability to revive and refresh the skin.
20. First Aid Beauty
First Aid Beauty was founded in 2009 and has quickly become a go-to brand for those with sensitive skin. The brand’s use of clean and safe ingredients has gained praise for its effectiveness in treating various skin concerns. Their Ultra Repair Cream and Facial Radiance Pads are two of their best-selling products that have gained a cult following for their gentle yet effective formulas.
21. Lancôme
Lancôme was founded in 1935 and has since become a top luxury skincare brand. The brand’s use of high-quality and innovative ingredients has led to the development of luxurious and effective products. Their Advanced Génifique Youth Activating Serum and Visionnaire Advanced Skin Corrector are two of their best-selling products that have gained a loyal following for their anti-aging benefits.
22. Sunday Riley
Sunday Riley was founded in 2009 and has quickly gained a cult following for its high-performance and clean skincare products. The brand’s use of advanced technology and powerful ingredients has led to the development of products that are loved by many. The Good Genes All-In-One Lactic Acid Treatment and Luna Sleeping Night Oil are two of their best-selling products that have become staples in many people’s skincare routines.
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